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FLASH GENE
Symbol EHMT2 contributors: mct/pgu - updated : 16-06-2015
HGNC name euchromatic histone-lysine N-methyltransferase 2
HGNC id 14129
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
significantly elevated in bladder carcinomas compared with nonneoplastic bladder tissues
tumoral     --over  
in aggressive lung cancer cells, and its elevated expression correlates with poor prognosis
constitutional     --over  
in the peripheral blood cells may support the notion of a restrictive chromatin state in autism spectrum disorders (ASD), similar to schizophrenia
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
importance of EHMT2 as a promising therapeutic target for various types of cancer
bloodhemoglobin 
novel therapeutic target for sickle cell disease (SCD)
ANIMAL & CELL MODELS