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FLASH GENE
Symbol BCL2L11 contributors: mct/npt/pgu - updated : 05-03-2017
HGNC name BCL2-like 11 (apoptosis facilitator)
HGNC id 994
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --other  
in amyotrophic lateral sclerosis
tumoral     --over  
constitutively overexpressed in multiple prostate and breast cancer cells as well as in primary tumor cells
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerreproductiveprostate
nhibition of prosurvival function of Bim may provide a new approach for efficient cancer therapy
ANIMAL & CELL MODELS
BIM -/- mice