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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

GAB1

contributors: mct - updated : 04-01-2014

HGNC name	GRB2-associated binding protein 1
HGNC id	4066

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer digestive oesophagus reducing GAB1 function may sensitize head and neck squamous cell carcinoma (HNSCC) to EGFR inhibitors, hence representing a new therapeutic target HNSCC treatment in combination with EGFR targeting agents

ANIMAL & CELL MODELS