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FLASH GENE
Symbol ASB2 contributors: mct - updated : 02-06-2021
HGNC name ankyrin repeat and SOCS box-containing 2
HGNC id 16012
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --low  
loss of ASB2 impairs cardiomyocyte differentiation and leads to congenital double outlet right ventricle
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • Asb2 knockout mice have placental defects, that subsequently result in failure to form a normal cardiac septum, and thereby result in embryo mortality