Symbol
| ASB2
| contributors: mct - updated : 02-06-2021
|
HGNC name
| ankyrin repeat and SOCS box-containing 2
|
HGNC id
| 16012
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --low
|  
|
loss of ASB2 impairs cardiomyocyte differentiation and leads to congenital double outlet right ventricle | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
| | | |
| Asb2 knockout mice have placental defects, that subsequently result in failure to form a normal cardiac septum, and thereby result in embryo mortality |