Other morbid association(s)
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Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
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tumoral
| germinal mutation
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in myelodysplasia, with increased ring sideroblasts, that is, refractory anaemia with ring sideroblasts (RARS) and refractory cytopenia with multilineage dysplasia | tumoral
| somatic mutation
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probably occur during chronic lymphocytic leukemia development | tumoral
| somatic mutation
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are prevalent in low-risk myelodysplastic syndromes with ring sideroblasts | tumoral
| somatic mutation
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in chronic lymphocytic leukemia | tumoral
| somatic mutation
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in patients with myelodysplastic syndrome, with myelodysplastic/myeloproliferative neoplasms and with AML | constitutional
| somatic mutation
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more than 90% of the patients with Refractory anemia with ring sideroblasts (RARS) carry somatic mutations in SF3B1 | |