Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SLC7A11 contributors: mct - updated : 08-03-2022
HGNC name solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
HGNC id 11059
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral       loss of function
promotes cancer cell survival upon glucose starvation
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • SLC7A11 may be a vital biomarker for the diagnosis and prognosis in laryngeal squamous cell carcinoma (LSCC)
  • overexpression might be a novel biomarker and a potential unfavorable prognostic factor
  • Therapy target
    SystemTypeDisorderPubmed
    cancerlung 
    targeting SLC7A11 appears to be a potentially significant method for LSCC treatment
    cancerdigestiveliver
    potential therapeutic target for liver carcinoma
    ANIMAL & CELL MODELS