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FLASH GENE
Symbol NNAT contributors: mct - updated : 29-09-2010
HGNC name neuronatin
HGNC id 7860
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
by aberrant hypermethylation in pediatric acute leukemia
tumoral     --over  
in several pituitary adenomas, including ACTH-producing, GH-producing, and nonfunctioning adenomas, but hardly detected in other brain tumors
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • aberrant expression of NNAT and TNC was a useful marker for distinguishing malignant peripheral nerve sheath tumor (MPNST) from benign neurofibroma
  • may be useful as a prognostic marker for lung adenocarcinoma
  • Therapy target
    ANIMAL & CELL MODELS