Symbol
| LONP1
| contributors: mct - updated : 26-01-2017
|
HGNC name
| lon peptidase 1, mitochondrial
|
HGNC id
| 9479
|
corresponding disease(s)
|
CODAS
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --over
|  
|
is a poor prognosis marker in human colorectal cancer and melanoma | |
Susceptibility
|
to Congenital diaphragmatic hernia (CDH) |
Variant & Polymorphism
other
| CDH probands with LONP1 variants had higher mortality in the neonatal period compared with other children with CDH |
|
|
Candidate gene
Marker
Therapy target
| | | |
| inactivation of Lonp1 in mouse embryonic lung epithelium leads to disrupted lung development and full lethality at birth |