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FLASH GENE
Symbol CARM1 contributors: mct/pgu - updated : 25-11-2015
HGNC name coactivator-associated arginine methyltransferase 1
HGNC id 23393
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in prostate carcinoma as well as androgen-independent prostate carcinoma
tumoral     --over  
in high-grade prostatic intraepithelial neoplasia
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
  • being a potential new target in the treatment of estrogen-dependent breast cancer
  • SystemTypeDisorderPubmed
    cancerreproductivebreast
    potential new target in the treatment of estrogen-dependent breast cancer
    ANIMAL & CELL MODELS
    loss of estrogen receptor (ER) activity in CARM1-deficient mouse embryonic fibroblast cells