Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SMAD2 contributors: mct/npt/pgu - updated : 24-05-2017
HGNC name SMAD family member 2
HGNC id 6768
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral somatic mutation      
in colorectal, hepatocellular and lung carcinomas
tumoral   LOH    
in cervical cancer
constitutional     --over  
ER stress in HSCs (Hepatic stellate cells) promotes liver fibrosis by inducing overexpression of SMAD2
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
digestiveliver 
may be a potential therapeutic target for the treatment of hepatic fibrosis
ANIMAL & CELL MODELS