Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol YWHAE contributors: mct/ - updated : 17/12/2008
HGNC name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
HGNC id 12851
ASSOCIATED DISORDERS
corresponding disease(s) MDS , DEL17P13D , DUP17P13
related resource MITOP database
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in gastric cancer
tumoral   deletion    
in small cell lung cancer
constitutional     --low  
synaptic reduction of DISC1 and YWHAE is developmentally correlated with the age-dependent decrease in striatal spine density
Susceptibility to schizophrenia
Variant & Polymorphism SNP SNP which influence the expression of 14-3-3 epsilon RNA and protein, is associated with schizophrenia and seems to work protectively
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS