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FLASH GENE
Symbol PEPD contributors: npt/SGE - updated : 02-02-2010
HGNC name peptidase D
HGNC id 8840
ASSOCIATED DISORDERS
corresponding disease(s) PEPD
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral        
increased serum prolidase activity may be associated with endometrial cancer and may be related to local invasion of endometrial cancer (Arioz 2009)
Susceptibility
Variant & Polymorphism
Candidate gene
  • serum prolidase activity can accurately predict the degree and stage of all histological lesions in non-alcoholic fatty liver disease (Kayadibi 2009)
  • serum prolidase activity is significantly associated with the presence and severity of coronary artery disease and elevated activity might be an independent predictor of coronary atherosclerosis (Yildiz 2008)
  • the presence of atrial fibrillation in patients with severe mitral stenosis may be associated with the plasma prolidase activity, tissue and plasma oxidative parameters (Rabus 2008)
  • an elevated pleural fluid and serum prolidase activity in patients with tuberculous (TB) pleurisy compared with non-TB pleurisy group (Ipcioglu 2008)
  • serum prolidase activity is associated with the presence hypertension independent of left ventricular hypertrophy (Demirbag 2007)
  • Marker
    Therapy target
    ANIMAL & CELL MODELS