Symbol
| SPI1
| contributors: mct - updated : 24-10-2017
|
HGNC name
| spleen focus forming virus (SFFV) proviral integration oncogene spi1
|
HGNC id
| 11241
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
| deletion
|  
|  
|
in acute myeloid leukemia | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
|
System | Type | Disorder | Pubmed |
immunology | inflammatory | | |
is a potential target for the treatment of immune-related diseases |
| | | |
| mice deficient in both Spib and Spi1 in the B-cell lineage had reduced frequencies of B cells as well as impaired B-cell differentiation, and developed pre-B cell acute lymphoblastic leukemia before 30 weeks of age |