Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --over
|  
|
in the dysfunctional heart, and in failing myocardium may have unique significance due to its nuclear localization | constitutional
|  
|  
|  
| loss of function
|
deficiency linked to early Alzheimer disease (AD) (Liu 2009) | constitutional
|  
|  
| --low
|  
|
impairs presynaptic M2 autoreceptor desensitization, which leads to a reduced acetylcholine release, axonal/synaptic degenerative changes, and associated amnestic, mild cognitive impairment | constitutional
|  
|  
| --over
|  
|
in heart failure (HF) | |