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FLASH GENE
Symbol GRIK5 contributors: mct - updated : 08-04-2019
HGNC name glutamate receptor, ionotropic, kainate 5
HGNC id 4583
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
of GRIK4, and GRIK5 in the hippocampus of patients with temporal lobe epilepsy (TLE)
constitutional     --low  
reduced genetically predicted expression of GRIK5 with comorbid vascular and eye diseases
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • Grik5-deficient embryos fail to pattern blood vessels in the brain, and this failure results in fewer, smaller branches