Symbol
| GRIK5
| contributors: mct - updated : 08-04-2019
|
HGNC name
| glutamate receptor, ionotropic, kainate 5
|
HGNC id
| 4583
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
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constitutional
|  
|  
| --over
|  
|
of GRIK4, and GRIK5 in the hippocampus of patients with temporal lobe epilepsy (TLE) | constitutional
|  
|  
| --low
|  
|
reduced genetically predicted expression of GRIK5 with comorbid vascular and eye diseases | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
| | | |
| Grik5-deficient embryos fail to pattern blood vessels in the brain, and this failure results in fewer, smaller branches |