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FLASH GENE
Symbol ACVRL1 contributors: mct/pgu - updated : 27-02-2015
HGNC name activin A receptor type II-like 1
HGNC id 175
ASSOCIATED DISORDERS
corresponding disease(s) ORW2
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --low  
with EGFL7 showed lower expression in early-onset pre-eclampsia versus late-onset pre-eclampsia
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • deletion of Alk1 in endothelial cell (EC) in adult mice leads to an increased local EC proliferation during brain angiogenesis and de novo brain arteriovenous malformations (AVMs)