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FLASH GENE
Symbol SLC1A5 contributors: mct - updated : 02-04-2019
HGNC name solute carrier family 1 (neutral amino acid transporter), member 5
HGNC id 10943
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in esophageal cancer
tumoral     --over  
significantly in colorectal cancer compared with normal mucosa tissues
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerdigestiveoesophagus
inhibition of esophageal cancer growth by targeting SLC1A5 could, therefore, be used as a preoperative therapy for esophageal cancer
cancerdigestivecolon
SLC1A5 could be a novel therapeutic target against KRAS-mutant colorectal cancer
ANIMAL & CELL MODELS