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FLASH GENE

Symbol

CDK11A

contributors: mct/pgu - updated : 27-06-2016

HGNC name	cyclin-dependent kinase 11A
HGNC id	1730

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral   deletion     in neuroblastoma constitutional     --low   caused defective chromosome congression, premature sister chromatid separation, permanent mitotic arrest and cell death

Susceptibility

to type 2 diabetes in a Han Chinese cohort

Variant & Polymorphism SNP	SNP11 strongly associated with female patients with T2D

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS