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FLASH GENE
Symbol LAMB3 contributors: mct - updated : 21-09-2011
HGNC name laminin, beta 3
HGNC id 6490
ASSOCIATED DISORDERS
corresponding disease(s) EBJ1B , EBJ2B
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --other  
expressed in non small cell lung cancer (coexpression with LAMC2)
tumoral     --over  
of LAMB3 and LAMC2 by promoter demethylation in gastric cancer
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • evaluation of LAMB3 and COL7A1 mRNA expression is useful for predicting the malignant properties of esophageal squamous cell carcinoma
  • Therapy target
    ANIMAL & CELL MODELS