Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

EIF5A2

contributors: mct - updated : 23-08-2010

HGNC name	eukaryotic translation initiation factor 5A2
HGNC id	3301

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma tumoral     --over   in ovarian and colorectal cancer

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer digestive liver targeting EIF5A hypusination by GC7 inhibitor or EIF5A2 by RNA interference (RNAi) may offer new therapeutic alternatives to hepatocellular carcinoma patients

ANIMAL & CELL MODELS