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FLASH GENE
Symbol EIF5A2 contributors: mct - updated : 23-08-2010
HGNC name eukaryotic translation initiation factor 5A2
HGNC id 3301
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma
tumoral     --over  
in ovarian and colorectal cancer
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerdigestiveliver
targeting EIF5A hypusination by GC7 inhibitor or EIF5A2 by RNA interference (RNAi) may offer new therapeutic alternatives to hepatocellular carcinoma patients
ANIMAL & CELL MODELS