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FLASH GENE
Symbol WFDC1 contributors: mct/npt - updated : 16-10-2009
HGNC name WAP four-disulfide core domain 1
HGNC id 15466
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
in senescent fibroblasts (Madar 2009)
constitutional     --low  
but not frequently mutated in prostate cancer (Watson 2004)
tumoral   LOH    
in hepatocellular carcinoma
Susceptibility
Variant & Polymorphism
Candidate gene downregulation of WFDC1 might serve as a biomarker for cellular transformation (Madar 2009)
Marker
Therapy target
ANIMAL & CELL MODELS