Symbol
| UTS2
| contributors: mct - updated : 20-03-2013
|
HGNC name
| urotensin 2
|
HGNC id
| 12636
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --low
|  
|
in patients with heart failure and in patients with renal diseases | constitutional
|  
|  
| --over
|  
|
of TAC3 and UTS2 in the plasma of pre-eclamptic women | |
Susceptibility
|
to NIDDM to myocardial infarction in individuals with or without conventional coronary risk factors |
Variant & Polymorphism
other
| S89N polymorphism is associated with the development of type 2 diabetes, via insulin sensitivity, in Japanese subjects |
|
polymorphisms associated with myocardial infarction in individuals with or without conventional coronary risk factors |
|
|
Candidate gene
Marker
| important marker of severity of portal hypertension in children | Therapy target
|
System | Type | Disorder | Pubmed |
miscelleaneous | urinary | | |
UTS2/UTS2R pathway may represent a novel therapeutical target in erectile dysfunction | digestive | liver | | |
potential therapeutic target in the chronic liver disease |
| | |
| 2DM mice showed increased Uts2/Uts2r content, in skeletal muscle |