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FLASH GENE
Symbol MAGEC2 contributors: mct - updated : 16-10-2019
HGNC name melanoma antigen family C, 2
HGNC id 13574
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility to chondromalacia
Variant & Polymorphism SNP
  • rs188900564 in the MAGEC2 associated with chondromalacia
  • Candidate gene
  • MAGEC2/CT-10 may be a good candidate for peptide vaccination in patients with hepatocellular carcinoma
  • Marker
  • expression of MAGEC1/CT7 and MAGEC2/CT10 in osteolytic lesions of myeloma patients can be used for diagnostic, prognostic, as well as immunotherapeutic purposes
  • Therapy target
    SystemTypeDisorderPubmed
    cancerhemopathy 
    MAGEC2-specific immunotherapies have the potential to eradicate the most malignant cells within the myeloma tumour bulk leading to durable clinical responses
    cancerreproductivebreast
    targeting MAGEC2 may provide a novel therapeutic strategy for breast cancer treatment
    cancerreproductiveprostate
    potential target for adjuvant and palliative immunotherapy in patients with prostate cancer
    ANIMAL & CELL MODELS