Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol KLF8 contributors: mct - updated : 22-02-2012
HGNC name Kruppel-like factor 8
HGNC id 6351
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional   translocation --low  
in a core of non syndromic mental retardation with translocation t(X;21)(p11.2;q22.3)
tumoral        
playing an important role in human breast cancer invasion and metastasis
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
co-targeting PARP1 and KLF8 (or other potential PARP1-interacting KLFs) as a novel anti-cancer therapeutic strategy
ANIMAL & CELL MODELS