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FLASH GENE
Symbol ARHGEF2 contributors: shn - updated : 06-09-2017
HGNC name Rho/Rac guanine nucleotide exchange factor (GEF) 2
HGNC id 682
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
contributes to the tumor progression phenotype associated with the TP53 mutation
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
genetic knockdown of mouse Arhgef2 in cortical precursors either in culture or in vivo inhibits neurogenesis and maintained cells as cycling radial precursors