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FLASH GENE

Symbol

FLOT1

contributors: mct/shn - updated : 10-05-2013

HGNC name	flotillin 1
HGNC id	3757

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

knockdown of flotillin-1/reggie-2 results in reduced EGF-induced phosphorylation of specific tyrosines in the EGF receptor and in inefficient activation of the downstream mitogen-activated protein kinase and Akt signaling