Symbol
| CRYAB
| contributors: mct/shn - updated : 02-10-2012
|
HGNC name
| crystallin, alpha B
|
HGNC id
| 2389
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
 
|  
|  
| --over
|  
|
in Alexander disease | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
| | | |
| Cryab-/- mice showed worse experimental autoimmune encephalomyelitis at the acute and progressive phases, with higher Th1 and Th17 cytokine secretion from T cells and macrophages, and more intense central nervous system inflammation ( | |
AxD mouse models that loss of Cryab results in increased mortality ( |