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FLASH GENE
Symbol MTBP contributors: shn - updated : 21-03-2012
HGNC name Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
HGNC id 7417
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • a potential biomarker for cancer progression
  • Therapy target
    ANIMAL & CELL MODELS
  • MTBP downmodulation leads to an abbreviated metaphase and insufficient mitotic arrest, abnormal chromosome segregation, aneuploidy, decreased cell proliferation, senescence, and cell death (