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FLASH GENE
Symbol MRPS30 contributors: mct/npt - updated : 12-07-2008
HGNC name mitochondrial ribosomal protein S30
HGNC id 8769
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • not showing any known motif or protein domain
  • specific to mitochondrial ribosomes not in prokaryotes
  • HOMOLOGY
    interspecies homolog to murine Mrps30
    homolog to E.Coli 30S subunit proteins
    intraspecies homolog to G-gallu proapoptotic protein p52
    Homologene
    FAMILY
  • ribosomal protein S30P family
  • CATEGORY regulatory , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    text mitochondrial ribosome
    basic FUNCTION
  • mitochondrial proteins biosynthesis
  • ribosomal structure and biogenesis
  • involved in cellular apoptotic signaling pathway
  • CELLULAR PROCESS cell life, cell death/apoptosis
    protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the small subunit (28S) of the mitochondrial ribosome, including two RNA molecules and 78 MRPs among which 31 proteins for the small subunit
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to estrogen receptor positive breast cancer with good prognosis
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS