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FLASH GENE
Symbol COQ7 contributors: mct/npt - updated : 07/11/2008
HGNC name coenzyme Q7 homolog, ubiquinone (yeast)
HGNC id 2244
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • three hydrophobic regions N terminal, central and C terminal
  • a putative discrimination of mitochondrial targeting sequence (hTTDISC)
    • HOMOLOGY
    interspecies homolog to yeast S.cerevisiae cat5p
    homolog to C.elegans longevity gene clk1
    Homologene
    FAMILY
  • di-iron containing oxidases/hydroxylases family
    • CATEGORY enzyme , transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,membrane
    intracellular,nucleus
    basic FUNCTION
  • catalyzes the production of coenzyme Q (CoQ) in mitochondria
  • involved in ubiquinone biosynthesis and hence, is required for respiration and gluconeogenesis
  • functioning as a hydroxylase
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS electron transport
    PATHWAY
    metabolism carbohydrate
    signaling
    gluconeogenesis
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS