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FLASH GENE
Symbol CACNG1 contributors: mlc - updated : 30-11-2007
HGNC name calcium channel, voltage-dependent, gamma subunit 1
HGNC id 1405
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY PMP-22/EMP/MP20 family, CACNG subfamily
CATEGORY transport channel
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • subunit of the dihydropyridine (dhp) sensitive calcium channel, playing a role in excitation-contraction coupling
  • functions as an endogenous Ca2+ antagonist whose task may be to minimize Ca2+ entry and Ca2+ release under stress-induced conditions favoring plasmalemma depolarization
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS