basic FUNCTION
| playing a necessary role for the generation of mature myelin-gene-expressing oligodendrocytes within the CNS (Emery 2009) |
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transcriptional regulator vital for the generation of myelinating oligodendrocytes, with an analogous role in the CNS to that of EGR2 in the PNS (Emery 2009) |
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is required for the generation of CNS myelination during development and also for its maintenance in the adult |
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is a novel example of a membrane-associated transcription factor and provide a direct molecular mechanism for its regulation of oligodendrocyte differentiation and CNS myelination |