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FLASH GENE
Symbol CA14 contributors: - updated : 02-12-2004
HGNC name carbonic anhydrase XIV
HGNC id 1372
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a N terminal signal sequence,two cysteine residues in the CA extracellular domain and a C terminal transmembrane segment
conjugated MetalloP
isoforms Precursor
HOMOLOGY
intraspecies homolog to CA12,highly
Homologene
FAMILY eukaryotic-type carbonic anhydrase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic
basic FUNCTION
  • carbonic anhydrase 14. reversibly hydrating Co2 in cellular ion transport and pH homeostasis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS homeostasis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    zinc Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS