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FLASH GENE
Symbol ACSL6 contributors: - updated : 17-09-2004
HGNC name acyl-CoA synthetase long-chain family member 6
HGNC id 16496
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
AMP binding enzyme domain
HOMOLOGY
interspecies homolog to murine Facl6
Homologene
FAMILY
  • ATP-dependent AMP binding enzyme family
  • long-chain fatty-acid-coenzyme A ligase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION extracellular
        intracellular
    intracellular,cytoplasm,organelle,mitochondria,outer
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,peroxisome
    intracellular,cytoplasm,cytosolic,microsome
    basic FUNCTION
  • playing a role in fatty acid metabolism in brain and the acyl-CoA produced maybe utilized exclusively for the synthesis of the brain lipid
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding, cofactor, nucleotide,
  • magnesium Mg2+
  • AMP
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS