basic FUNCTION
| acting as a transcriptional repressor |
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may play like a bridging molecule between DNMT3B |
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and other co-repressor protein |
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enhancing the transcriptional repression mediated by DNMT3B when DNMT3B is directly targeted to DNA |
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ZHX1, ZHX2, ZHX3 have biological roles in cell cycle control by acting as co-repressors of the transcriptional regulator Nuclear Factor Y |
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nuclear transcription repressor known to be involved in cell differentiation and tumorigenesis |
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plays crucial roles in the progression of glioblastoma |