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FLASH GENE
Symbol ZNF263 contributors: SGE/npt - updated : 04-05-2009
HGNC name zinc finger protein 263
HGNC id 13056
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal SCAN box leucine-rich mediating self-association and oligomerization
  • a finger-associated structural motif
  • the A element of the Krüppel-associated box (KRAB)
  • nine zinc finger motifs C2H2 (Krüppel) type
  • secondary structure two alpha helices
    conjugated MetalloP
    HOMOLOGY
    interspecies homolog to murine Zfp263
    homolog to C.elegans F42G4.3A
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • SCAN subfamily
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • can have both positive and negative effects on transcriptional regulation of its target genes (Frietze 2010)
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS