Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol NEK3 contributors: - updated : 06-06-2006
HGNC name NIMA (never in mitosis gene a)-related kinase 3
HGNC id 7746
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • twelve conserved regions characteristic of protein kinase catalytic domain
  • conjugated PhosphoP
    HOMOLOGY
    interspecies ortholog to Aspergillus nidulans NIMA
    homolog to rattus Nek3 (75.4pc)
    homolog to murine Nek3 (75.1pc)
    Homologene
    FAMILY
  • Ser/Thr protein kinase family
  • NIMA subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule,mitotic spindle
    intracellular,nucleus
    basic FUNCTION
  • may play a role in mitotic regulation
  • CELLULAR PROCESS cell cycle, division, mitosis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding, cofactor, nucleotide,
  • Mg2+
  • ATP
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS