basic FUNCTION
| protein kinase,double stranded RNA dependent inhibitor,particularly of P58 |
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may function as zinc-dependent sequence-specific DNA-binding factors with roles in proliferation, apoptosis, cell cycle, chromosome segregation, chromatin modification, and transcriptional |
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synergistically enhances type I IFN production mediated by a signal activated- or constitutively active form of regulation of DDX58 |
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novel positive regulator controlling the DDX58-IFN production system through protein stability control |
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inhibits ubiquitination of DDX58 and suppresses proteasomal degradation of DDX58 proteins, thereby enhancing DDX58-mediated signaling pathways for IFNB synthesis |
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novel positive regulator of DDX58-mediated antiviral signaling pathways |