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FLASH GENE
Symbol NME6 contributors: - updated : 25-08-2007
HGNC name non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase)
HGNC id 20567
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • putative leucine-zipper domain
  • a Kpn (Drosophila Killer of prune) loop
  • a RGD domain
  • a C terminal extension preceded by the YEEEEP motifs
  • HOMOLOGY
    Homologene
    FAMILY
  • NM23 nucleoside diphosphate kinase gene family
  • NDP kinase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    text colocalized with mitochondria
    basic FUNCTION
  • catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates
  • playing a role in regulation of cell growth and cell cycle progression
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    nucleotide
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Mg2+
  • ATP
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS