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FLASH GENE
Symbol SLC25A15 contributors: mct/npt - updated : 13-11-2009
HGNC name solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
HGNC id 10985
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • three SOLCAR repeats
  • HOMOLOGY
    interspecies homolog to murine Slc25a15
    intraspecies homolog to SLC25A2
    Homologene
    FAMILY
  • mitochondrial carrier family
  • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,membrane
    basic FUNCTION
  • involved in the ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix
  • mitochondrial carrier protein, which catalyzes the
  • electroneutral exchange of ornithine for citrulline plus an H1 ion (Tessa 2009)
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS mitochondrial transport
    PATHWAY
    metabolism aminoacid
    signaling
    urea cycle
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) HHH
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS