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FLASH GENE
Symbol MARCO contributors: - updated : 12-02-2004
HGNC name macrophage receptor with collagenous structure
HGNC id 6895
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a short N terminal cytoplasmic domain with 2 potential glycosylation sites.
  • a transmembrane domain followed by an extracellular part with a spacer domain III
  • a triple helical collagenous domain
  • a C terminal scavenger receptor cysteine-rich domain
  • HOMOLOGY
    interspecies homolog to murine Marco
    Homologene
    FAMILY
    CATEGORY immunity/defense , receptor
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION playing a role in innate immune response
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule other,
    binding Gram-positive and Gram- negative bacteria
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS