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FLASH GENE
Symbol MINPP1 contributors: npt - updated : 23-01-2008
HGNC name multiple inositol polyphosphate histidine phosphatase, 1
HGNC id 7102
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • conserved active site of histidine phosphatases
  • a C terminal consensus sequence, retaining the enzyme in the endoplasmic reticulum
    • HOMOLOGY
    interspecies homolog to murine Minpp1
    Homologene
    FAMILY
  • phosphoglycerate mutase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    basic FUNCTION
  • playing a role in the tumorigenesis of at least a subset of malignant follicular thyroid
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral germinal mutation LOH    
    in follicular thyroid carcinoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS