Selected-GenAtlas references SOURCE GeneCards NCBI Gene Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol GUCY1B2 contributors: npt - updated : 04-07-2006
HGNC name guanylate cyclase 1, soluble, beta 2
HGNC id 4686
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
mono polymer heteromer , dimer
HOMOLOGY
interspecies homolog to C.elegans k08d10.2
ortholog to rattus beta2 subunit
Homologene
FAMILY
  • adenylyl cyclase class-4/guanylyl cyclase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    text soluble forms and membrane-associated receptor forms
    basic FUNCTION
  • guanylate cyclase, beta 2 subunit
  • inhibiting the nitric oxide (No) stimulated activity of the alpha 1/beta 1 form of guanylate cyclase
  • maybe involved in the regulation of blood pressure
  • playing a major role in the cardiovascular system as a receptor for nitric oxide
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cardiovascular
    PATHWAY
    metabolism
    signaling
    a component
  • an alpha and beta chains
  • INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • GTP
  • protein
    cell & other
    REGULATION
    activated by nitric oxide in the presence of magnesium or manganese ions
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS