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FLASH GENE
Symbol AKR7A2 contributors: - updated : 26-04-2005
HGNC name aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
HGNC id 389
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to rattus norvegicus gene
Homologene
FAMILY aldo/keto reductase 2 family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION
  • aldo-ketoreductase,(especially aflatoxin B1-aldehyde reductase), catalyzing the reduction of 2-carboxybenzaldehyde (2-CBA) and related molecules
  • involved in endogenous detoxication pathway
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism drug , lipid/lipoprotein
    signaling
    detoxication
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor, nucleotide,
    NADPH
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS