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FLASH GENE
Symbol GALR3 contributors: mct - updated : 02-10-2007
HGNC name galanin receptor 3
HGNC id 4134
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
seven transmembrane segments (7TM) receptor
HOMOLOGY
Homologene
FAMILY G protein coupled receptor superfamily
CATEGORY receptor
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • involved predominantly in signaling through inhibition of adenylate cyclase
  • couple to their intracellular effector through distinct signaling pathways
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein receptor for the hormone galanin
    cell & other i5 linked to voltage gated calcium channel
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to alcoholism
    Variant & Polymorphism SNP significant association with alcoholism that was driven by one SNP (rs3,091,367)
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS