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FLASH GENE
Symbol TNP2 contributors: mct - updated : 09-09-2006
HGNC name transition protein 2 (during histone to protamine replacement)
HGNC id 11952
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Tnp2
Homologene
FAMILY family of transition proteins
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • may be involved in chromatin condensation during spermiogenesis
  • conversion of nucleosomal chromatin to the compact, nonnucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins
  • basic chromosomal proteins that replace the histones during chromatin remodeling
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS