basic FUNCTION
| involved in the control of cell division and growth regulation |
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concentrates potentially WNT3A and WNT5A to the vicinity of their specific receptors in different membrane microdomains, thereby regulating distinct Wnt signaling |
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astrocyte-secreted signal sufficient to induce functional synapses between purified retinal ganglion cell neurons |
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GPC4 and GPC6 are astrocyte-derived molecules necessary and sufficient to promote glutamate receptor clustering and receptivity and to induce the formation of postsynaptically functioning CNS synapses |
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required for the maintenance of adult neural stem cell fate |
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acts at the interface of extrinsic and intrinsic signal regulation to fine tune stem cell fate |
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role of GPC4 and WNT5B in chondrocyte stacking underlying craniofacial cartilage morphogenesis |