Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SYNGR1 contributors: - updated : 28-08-2007
HGNC name synaptogyrin 1
HGNC id 11498
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • four transmembrane segments with cytoplasmic N and C termini
  • two conserved cysteine residues between TM1 and TM2
  • a MARVEL domain
  • HOMOLOGY
    interspecies homolog to murine syngr1
    Homologene
    FAMILY synaptogyrin family
    CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,vesicle
    text
  • vesicle protein of synaptic vesicles
  • associated with presynaptic vesicles in neuronal cells
  • basic FUNCTION
  • involved in synaptic plasticity without being required for synaptic transmission
  • involved in presynaptic pathways, and may be in the pathogenesis of schizophrenia
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to schizophrenia (SCZ) and bipolar disorder
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS