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FLASH GENE
Symbol DNAH17 contributors: mct - updated : 26-08-2019
HGNC name dynein, axonemal, heavy polypeptide 17
HGNC id 2946
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
CATEGORY motor/contractile
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytoskeleton,microtubule
basic FUNCTION
  • outer dynein arm heavy chain having ATPase activity
  • involved in intracellular movement of organelles and vesicles or in the orientation of the mitotic spindle apparatus
  • CELLULAR PROCESS cell cycle, division
    cell communication
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism
    signaling
    a component axonemal constituent (outer arm)
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other interacting with microtubules
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) SPGF39
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
  • could be a promising biomarker for tumor thrombosis in HCC patients
  • Therapy target
    ANIMAL & CELL MODELS