basic FUNCTION
| potential mediator in the central feedback mechanism, that regulates feeding behavior |
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hypothalamic neuropeptide precusor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing |
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regulating feeding and sleeping |
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involvement of hypocretin in sleep disorders in dementia with Lewy bodies |
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are critical for the normal temporal structure of sleep and wakefulness, they also appear to be important in regulating baseline blood pressure and possibly in modulating the effects of sleep on blood pressure |
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potently influences dopamine neuron activity, in part by modulating responses to medial prefrontal cortex inputs |
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hypothalamic polypeptides such as PMCH and HCRT are promoters of sleep-wake regulation and energy homeostasis and are found to impact on cognitive performance |